Molecular Cancer Research Group

Description of Research Group

Major project: Genotoxicity and repair of epigenetic base damages induced by methylation.

Other projects: 5-Formyluracil mutagenesis promoted by excision repair; DNA strand incision by uracil-DNA glycosylases.

Technology, expertise and equipment

Recombinant protein expression and purification; binding studies ITC, MST, DNA repair assays, denaturing PAGE, TLS, Western blotting, dot blotting, enzyme kinetics