Description of Research Group
The chromatome team focuses on epigenetic regulation in embryonic stem cells and cancer.
The main interest in our lab is to understand how gene activity is regulated by local composition (histone modifications and variants), chromatin structure and nuclear organisation. We uniquely combine in vitro and in vivo approaches to study these epigenetic mechanisms during in embryonic stem cell differentiation, in cancer cells and after exposure to drugs.
Eskeland is in the leader team of PharmaTox strategic research initiative at University of Oslo and a partner PI in the NoE Centre for Cancer Cell Reprogramming.
Technology, expertise and equipment
Tissue culture, Chromatin Immunoprecipitation, Biochemistry, Molecular Biology, Imaging, Bioinformatics